Best Answer # 1: from Gerald W. Edwards:
"The first commercial brewery in Woodstock, Ontario, was the 'Woodstock Brewery'. It was located at the south-west corner of Dundas and Norwich Streets. The owners were S & J Collins and they owned the brewery from 1857-1884. A succession of additional owners kept the business going until 1914. There was one brewery operating earlier in the county in 1852. It was run by John G. Arkell."

Extra Information from Quiz Committee:
Mr Larry Collens, the great grandson of the first proprietor, Stephen Collens (the correct spelling) sent us interesting extra details:

"Stephen Collens (1801-1878) moved from England to Hamilton, Ont, in 1836, where he worked in a brewery for a few years. He decided he wanted his own brewery, so after borrowing money from his employer, he moved to Woodstock, Ont. and built a brewery on the corner of Dundas St and Norwich Ave.

The building was made of white brick and his name was built into the Norwich side of the building in red brick. After Stephen's death, the brewery was run by his sons who later sold the business to a Mr P. Bernhart who in turn sold it to a Mr Otterbein, who converted part of the building into a foundry - hence burned the building down. End of brewery. Stephen Collens was my great grandfather." 

Source:
- Larry Collens, grandson of the original brewery's founder.